Solna, Sweden, May 10, 2017. Affibody AB (“Affibody”) today announced that it has decided to initiate Phase II development with ABY-035, which is the company’s proprietary psoriasis program.

Inmagene and Affibody have formed a strategic partnership to develop and commercialize izokebep (IMG-020 or ABY-035), a bispecific fusion protein targeting 

ABY-035 is a novel IL-17A targeting agent that utilizes the strengths of Affibody’s technology platform to create a very small protein drug (18 kDa, an eighth of an antibody) with very high apparent affinity to IL-17A (KD ~300fM) and antibody-like half-life. Affibody and Inmagene announce IND Clearance for izokibep (ABY-035) for the treatment of Non-infectious Non-anterior Uveitis San Diego, U.S., Shanghai, China, and Solna, Sweden, March 9, 2021. Affibody AB (“Affibody”) and Inmagene Biopharmaceuticals (“Inmagene”) today announced that the U.S. FDA [read more] 2021-02-19 ABY-035 is a novel bispecific agent, potently targeting both subunits of IL-17A as well as albumin, which has been specifically designed to utilize the strengths of Affibody’s technology platform to create a very small protein drug (18 kDa, an eighth of the size of an antibody) with very high apparent affinity to IL-17A (KD ~300fM) and antibody-like half-life due to the strong (KD ~50pM) binding affinity to serum albumin. Affibody AB (“Affibody”) and Inmagene Biopharmaceuticals (“Inmagene”) today announced that the U.S. FDA has cleared izokibep (ABY-035) to proceed to Phase 2 clinical development in Ankylosing Spondylitis (AS), a subset of Axial Spondyloarthritis (axSpA).

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“Our Phase 2 AFFIRM-35 study with ABY-035 has now reached the stage where we are starting to see the first results,” said David Bejker, CEO of Affibody. Affibody announces that it has decided to initiate Phase II development with ABY-035, which is the company’s proprietary psoriasis program. “This Affibody molecule, ABY-035, has been specifically designed to capture the unique aspects of the Affibody technology. It is a bi-specific construct with extraordinary affinity and confirmed antibody-like half-life. The initial results from our 2017-05-10 08:07 CEST Affibody To Initiate Phase II Psoriasis Trials For Lead Candidate ABY-035 Solna, Sweden, May 10, 2017. Affibody AB (“Affibody”) today announced that Each group consists of 8 subjects where 6 subjects will receive ABY-035 and 2 will receive placebo.

ABY-035 has been specifically designed to utilize the strengths of Affibody’s technology platform to create a very small protein drug (18 kDa, an eighth of the size of an antibody) with very high apparent affinity to IL-17A (KD ~300fM) and antibody-like half-life due to the strong (KD ~50pM) binding affinity to serum albumin. Affibody AB, a clinical stage biopharmaceutical company, announced the initiation of its 52-week trial investigating the novel bispecific IL-17A inhibitor ABY-035 in patients with psoriatic arthritis (PsA).

Jan 20, 2020 pharmacokinetics and immunogenicity of ABY-035 B.4.1, Name of organisation providing support, Affibody AB. B.4.2, Country, Sweden.

6.7. ABY-035 (Affibody).

Affibody AB (“Affibody”) and Inmagene Biopharmaceuticals (“Inmagene”) today announced that the U.S. FDA has cleared the novel interleukin-17 (IL-17) blocker izokibep (ABY-035) to proceed

The initial results from our 2017-05-10 08:07 CEST Affibody To Initiate Phase II Psoriasis Trials For Lead Candidate ABY-035 Solna, Sweden, May 10, 2017. Affibody AB (“Affibody”) today announced that Each group consists of 8 subjects where 6 subjects will receive ABY-035 and 2 will receive placebo.

Abstract: The present disclosure relates to a class of engineered polypeptides having a binding affinity for interleukin-17A (IL-17A), and provides an IL-17A  Find company research, competitor information, contact details & financial data for Affibody AB of Solna, Stockholm. Get the latest business insights from Dun  Affibody AB develops biopharmaceuticals products. The Company specializes in the discovery of a novel class of antibody mimetics that provide biodistribution  affibody is a clinical stage swedish biotech company focused on developing next generation biopharmaceuticals based on its unique proprietary technology Nov 30, 2014 The project aims to provide documentation necessary to start GMP manufacturing of the Affibody®-based RIT and subsequently start clinical trials  We supported the bioanalysis for ABY-035, a small protein drug of only 19 Affibody's technology platform to create an IL-17-specific ligand trap with a superior. 2020年5月15日 ABY-035是靶向IL-17和血清白蛋白的双特异性新型融合蛋白，由于其对IL-17A与 血清白蛋白都具有很高的亲和力（KD分别大约为300fM和50pM），  2019-07-16. Affibody Announces Interim Analysis in Phase 2 Psoriasis Trial of ABY-035 · Solna, Sweden, July 16, 2019. Affibody AB (“Affibody”), a clinical stage  Affibody is a Swedish biotech company developing next generation Affibody and Inmagene announce IND Clearance for izokibep (ABY-035) for the treatment  Affibody AB (“Affibody”), a clinical stage biopharmaceutical company, today process development and GMP manufacturing of Affibody's ABY-035 drug. Affibody and Inmagene announce IND Clearance for izokibep (ABY-035) for the treatment of Non-infectious Non-anterior Uveitis.
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Evaluate efficacy of ABY-035 vs placebo after 12w treatment 3. Evaluate efficacy, defined as PASI 90 response, of different dosing regimens of ABY-035 in subjects with moderate-to-severe plaque psoriasis after 24, 52, 76, … Affibody: ClinicalTrials.gov Identifier: NCT04713072 Other Study ID Numbers: ABY-035-202 : First Posted: January 19, 2021 Key Record Dates: Last Update Posted: January 20, 2021 Last Verified: January 2021 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: No Solna, Sweden, February 20, 2019. Affibody AB (“Affibody”), a clinical stage biopharmaceutical company developing a pipeline of innovative drug projects, today announced the completion of enrollment in the Company’s Phase 2 proof-of-concept study of ABY-035 for moderate-to-severe psoriasis (“AFFIRM-35”). Affibody Announces Initial Results from a Phase I Study of ABY-035 Solna, Sweden, May 4, 2016. Affibody AB (“Affibody”) today announced that it has completed the dose-escalation part of a Phase I study of ABY-035, which is the company’s proprietary psoriasis program.

Affibody Enters into Agreement with 3P Biopharmaceuticals for Production of ABY-035 2019-05-27 Solna, Sweden, May 27, 2019.
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kulturmiljö), 1653-4948 ; 2006:035) cop. Rök och Svanshals : Ödeshögs, Heda, Svanshals, Röks och Stora Åby socknar, Ödeshögs [Åby : Firma Anders Witt information], 2008. Affibody molecules targeting the epidermal growth factor

Partners eye additional applications in autoimmune diseases during 2021.

ABY-035 is a novel bispecific agent, potently targeting both subunits of IL-17A as well as albumin, which has been specifically designed to utilize the strengths of Affibody’s technology platform to create a very small protein drug (18 kDa, an eighth of the size of an antibody) with very high apparent affinity to IL-17A (KD ~300fM) and antibody-like half-life due to the strong (KD ~50pM

Recently, the he althy voluntee r dose escalatio n. Affibody har tecknat avtal med det kinesiska bioteknikbolaget Inmagene Biopharmaceuticals om ett strategiskt partnerskap för utveckling och kommersialisering av den biologiska läkemedelskandidaten ABY-035, som för närvarande är i en tysk dubbelblind, placebokontrollerad fas 2-studie mot psoriasis.

(73) Affibody AB, Voltavägen 13 161 02 Bromma, SE  kulturmiljö), 1653-4948 ; 2006:035) Åby 1936-2006: travbanan i Mölndal : de 70 första åren : Affibody molecules targeting the epidermal growth factor.